Research
Our group is dedicated to the understanding of chemical reactions, drugs and other biological species in their natural environment, using modern techniques of mass spectrometry and structural calculations.
Check below for projects that are currently in progress:
Reaction Intermediates
Online coupling of electrochemical cell using mass spectrometer for the study of intermediates of electrochemical reactions by vibrational spectroscopy of ions in the gas phase. Tatiana Casselli Penna.
Mechanistic elucidation of reactions of synthetic interest through the “fishing” of intermediates using the technique of infrared multifotonic dissociation spectroscopy (IRMPD). Francisco Wanderson Moreira Ribeiro.
Evaluation of the reaction mechanism of carbodiimide mediated processes by mass spectrometry. Eric Lobato Graef.
Biological systems
Evaluation of drugs, pro-drugs and bioactive compounds fragmentation mechanism and other reactive processes by electrospray ionization mass spectrometry (ESI-MS) and IRMPD spectroscopy. André Santos Fernandes, Guilherme Obeid and Milena Oliveira..
Instrumentation
Development of ionization sources for mass spectrometry including DESI, EASI, nanospray and paperspray with use of 3D printers. Tiago Laureno. and Tatiana Casselli Penna.
Microsolvation
Evaluation of the properties of reactivity and acidity / basicity in a microsolvation regime. André Filipe Rodrigues de Oliveira and Tatiana Casselli Penna.